Arachidonate 5-Lipoxygenase

An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.

Also Known As:

5 Lipoxygenase; Arachidonate 5 Lipoxygenase; Arachidonic Acid 5-Lipoxygenase; LTA4 Synthase; Leukotriene A Synthase; Leukotriene A4 Synthase; Leukotriene A4 Synthetase; 5-Lipoxygenase, Arachidonate; 5-Lipoxygenase, Arachidonic Acid; Arachidonic Acid 5 Lipoxygenase; Synthase, LTA4; Synthase, Leukotriene A; Synthase, Leukotriene A4; Synthetase, Leukotriene A4; 5-Lipoxygenase; Arachidonate:oxygen 5-oxidoreductase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Oxygenases: 333
      - Dioxygenases: 495
        Lipoxygenases: 264
        Arachidonate Lipoxygenases: 16
        Arachidonate 5-Lipoxygenase: 1268
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Metalloproteins: 164
    - Iron-Binding Proteins: 172
      - Nonheme Iron Proteins
        Lipoxygenases: 264
        Arachidonate Lipoxygenases: 16
        Arachidonate 5-Lipoxygenase: 1268

K Karlage Selected Research

K Karlage Research Topics

Disease

Drug/Important Bio-Agent (IBA)